You must survive four days by scavenging a new location, exploring the rooms, and collecting supply cards to fill your backpack. Listen carefully and use your hand to slam a stack where the top supply card matches the request. If you fail to fill a backpack or overcome the hazards you've encountered by the end of the day, you become a zombie. That doesn't mean your game is over as the undead can rise again and win by infecting the most stragglers! Zombie Slam is played over four rounds with all players acting simultaneously, and each round consists of ten turns.

There is also an optional smart device app to guide the play, which also turns Zombie Slam into a movie-like experience!